PRECLINICAL PROOF-OF-CONCEPT ADAPTED TO YOUR NEEDS
In order to support customers to translate preclinical project ideas into efficient experimental plans and conclusive clinical trials, we offer expert scientific support and preclinical lab services. Our services emphasise on pharmacology, translational science and scientific understanding.
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In Vitro
MVIC offers a wide range of in vitro services
MVIC offers a wide range of in vitro services including Cell-based Assays such as Mode-of-Action and efficacy assays, and Biomarker Analysis. We provide customized assays, and our experienced team will work together with you to determine, develop, and run the optimal assays for your studies and projects. We have fully equipped in vitro laboratories including cell culture facilities for both primary and secondary cell lines.
In Vivo
Extensive experience and expertise of designing, performing, evaluating, and reporting preclinical studies in an efficient and flexible way
MVIC provides a number of different animal models and technologies. We use defined protocols or adjust and modify protocols based on specific scientific questions that are to be addressed. We generate pharmacokinetic profiles in an individual animal, creating high robustness in your data. We can assist you with bioanalysis and ensure the best PK parameter determination using the industry-standard software Phoenix® WinNonlin®. For a better understanding of PK/PD relationship we perform modelling and dose predictions. We develop PD models and perform in vivo studies using most administration routes in rodents, including inhalation. Through close collaboration with formulation experts, we can ensure optimal formulations. We also perform imaging studies using different modalities including optical imaging, CT, MRI and PET.
Optimization and characterization of Aerosol Delivery for Efficacy and Toxicology Studies
MVIC has extensive experience of delivery to the lung and offers a wide range of technological solutions and experimental settings for preclinical inhalation studies. We have capabilities to conduct single and repeated dosing, using whole-body or nose-only inhalation exposure. Inhalation toxicology is another speciality.
Consultancy Services with Emphasis on Pharmacology, Translational Science and Business Development
In close collaboration with our customers, we develop strategic project plans and Target Product Profiles (TPP). We design preclinical studies and write study protocols and prepare the project to meet future regulatory issues. That includes translational medicine plans and biomarker plans. To ensure that you make the most of your business idea we can assist you in elaborating your business plan through market research and evaluation. Our extensive experience in the area allows us to give advice on licensing and early financing.